This chapter provides a brief overview of the overall structure by the Chief Editors of the Handbook of Open, Distance, and Digital Education (ODDE) published in Springer’s Major Reference Series. The handbook is organized along the lines of the 3M-Framework covering all important issues related to ODDE at the macro- (ODDE systems, theories, and methods), meso- (ODDE educational management and institutions), and micro- (teaching and learning) levels. Each level is addressed in one volume with two sections. Informed by the historical roots of ODDE, the editors and authors of this handbook are shaping the field of ODDE scholarship, theory, and practice.